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  • Treatment: Exercise & Movement
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Clinical RelevanceDOI 4 min read
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Patient-friendly summary

If you read nothing else

If you have long-term neck pain, exercising tends to ease it in the short term better than not exercising, and no single type of exercise is clearly the best — so pick one you'll stick with.

Bottom line

Several exercise types (motor control, Pilates, resistance, Tai Chi/Qigong, yoga) all help reduce chronic neck pain short-term versus no exercise, with no clear winner among them and uncertain long-term benefit.

Moderate evidence

Published

2023
3 years ago
Current

Evidence hierarchy

Meta-analysis
Systematic Review ◀ this study
RCT
Cohort
Case-Control
Case Report
Expert Opinion

Study participants

17,321 participants across 221 RCTs in 25 systematic reviews (overlap not accounted for)18 to 70 yearsNot reported

Adults aged 18–70 with chronic neck pain lasting 12 weeks or more

Full research — for clinicians and curious readers

Study Summary

This systematic review of systematic reviews (umbrella review) summarized the evidence on five exercise types — motor control exercise (MCE), Pilates, resistance training, traditional Chinese exercise (TCE: Tai Chi/Qigong), and yoga — for adults with chronic neck pain lasting at least 12 weeks. Across 25 included reviews (221 RCTs, 17,321 participants with overlap not accounted for), the authors found low to high certainty evidence that all five exercise types produce short-term improvements in pain compared with non-exercise controls, and that all except resistance training also improve disability short-term. When exercise types were compared head-to-head with one another, or assessed over the intermediate/long term, results were conflicting or showed no clear advantage of one type over another. The authors conclude no single optimal exercise type can be recommended, and note the included reviews varied widely in methodological quality.

70/100
Evidence StrengthModerate
Study Quality
Sample Size
Replication

Key Findings

FindingDetailImpact
All five exercise types reduced pain short-term versus non-exercise controlsNarrative analyses showed positive short-term effects on pain for MCE, Pilates, resistance training, TCE, and yoga compared with non-exercise controls (usual care, education, waitlist), with low to high certainty of evidence.High
All exercise types except resistance training improved short-term disability versus non-exercise controlsMCE, Pilates, TCE, and yoga showed positive short-term effects on disability compared to non-exercise controls; for resistance training, results on disability were varying with low certainty in the intermediate/long-term and no significant short-term meta-analytic effect (SMD = -0.91, 95%CI -2.22 to 0.39).High
No single exercise type was clearly superior to anotherWhen exercise types were compared head-to-head, results were conflicting or showed no advantage; MCE was the exception, showing positive short-term effects on pain (SMD = -0.25, 95%CI -0.38 to -0.13) and disability (SMD = -0.36, 95%CI -0.52 to -0.20) versus other exercises. The authors conclude no optimal exercise intervention can be recommended.High
Intermediate/long-term effects were uncertainIn the intermediate/long-term, results were mainly no effect or varying for both pain and disability, whether compared to non-exercise controls or other exercises. For yoga, no long-term results were available at all.High
Methodological quality of included reviews was often lowOf 25 reviews, 5 were high quality, 7 moderate, 8 low, and 5 critically low (13 of 25 rated critically low to low). The main AMSTAR-2 shortfall was a non-comprehensive literature search (only 13 of 25 scored 'yes' on item 4). The authors also reported finding numerous data errors when spot-checking SR/MA data against original RCTs.Medium
MCE showed a notably large short-term pain effect versus non-exercise controlsPooling two SRs using a non-exercising comparator gave a large short-term effect for MCE on pain intensity (SMD = -1.69, 95%CI -2.73 to -0.64; I2 = 5%) and disability (SMD = -2.26, 95%CI -3.13 to -1.39; I2 = 0%), though these estimates come from few reviews.Medium
Study Methodology
Study Design
Systematic review and meta-analysis of systematic reviews (umbrella review), PRISMA-guided, registered in PROSPERO (CRD42022336014); included SRs/MAs in which at least 75% of original studies were RCTs; AMSTAR-2 for quality and GRADE for certainty of evidence; narrative synthesis plus random-effects meta-analyses (standardized mean differences) where feasible
Sample Size
25 systematic reviews comprising 221 RCTs and 17,321 participants (overlap not accounted for; 125 unique original studies after accounting for overlap); 16 SRs contributed to meta-analyses
Duration
Searches conducted 29 April 2022, updated 28 June 2023; included reviews published 2010–2023; outcome follow-up classified as short-term (1 day to 3 months), intermediate-term (3 months to <1 year), and long-term (≥1 year)
Population
Adults aged 18–70 (mainly working-age) with chronic neck pain defined as lasting 12 weeks or more; reviews investigating whiplash-associated disorders as a primary population were excluded
Outcome Measures
Pain intensity · Disability · Standardized mean difference (SMD) · Statistical heterogeneity (I2) · AMSTAR-2 methodological quality · GRADE certainty of evidence · Corrected covered area (CCA) for overlap

Strengths

  • First systematic review of systematic reviews on various exercise types for chronic neck pain, to the authors' knowledge
  • Conducted by a large group of experienced researchers following PRISMA and Cochrane Back- and Neck Group recommendations
  • Comprehensive multi-database search (Ovid MEDLINE, Embase, Cochrane Library, SportDiscus, Web of Science) with no restrictions on year, comparator, or language
  • Formal quality (AMSTAR-2) and certainty-of-evidence (GRADE) appraisal applied throughout
  • Prospectively registered protocol (PROSPERO CRD42022336014) with no protocol deviations
  • Overlap between reviews quantified using corrected covered area (CCA)

Limitations

  • More than half of included reviews (13 of 25) were of critically low to low methodological quality, downgrading certainty of evidence
  • The authors relied on data as presented in the included reviews and reported encountering numerous data errors when spot-checking against original RCTs
  • High overlap of original studies across reviews for some exercise types (e.g., TCE CCA 41%, MCE high overlap), and for TCE there were more reviews (seven) than underlying RCTs
  • Substantial heterogeneity in exercise style, dose, duration, and comparator groups limited clinical recommendations; optimal dose could not be determined
  • Chinese-language systematic reviews were excluded due to lack of reading competence, which may have affected results
  • No long-term data were available for yoga; intermediate/long-term findings overall were sparse and inconsistent
  • Mind-related outcomes (e.g., quality of life, mood) were not assessed, only pain and disability

Key Takeaways for Patients

What This Means for You

  1. If you have long-lasting neck pain, doing exercise generally helps reduce pain in the short term more than doing no exercise at all.

  2. No single type of exercise — motor control/deep-neck exercises, Pilates, resistance training, Tai Chi/Qigong, or yoga — clearly beats the others, so you can reasonably choose a type you enjoy and will stick with.

  3. Benefits are clearest in the short term (up to about 3 months); the longer-term picture is less certain because fewer studies followed people that far.

  4. The best choice of exercise is one made together with your clinician, based on your preferences, since sticking with the program appears to matter for results.

  5. These findings come from reviews of varying quality, so they should be read as encouraging but not definitive.

Read the Full Paper

Access the complete peer-reviewed study from BMC Musculoskeletal Disorders

View Full Study

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