Study Summary
Background
Chronic pain is a major burden for people living with social and health inequities, who often face barriers to accessing appropriate care and may resort to unregulated drug use to self-manage their suffering. Myofascial dysfunction (MFD), involving fascial tension, muscle trigger points, and scar tissue restrictions, is frequently overlooked as a contributor to chronic pain. The Downtown East Side (DTES) of Vancouver, British Columbia, is home to a particularly vulnerable population with high rates of trauma, homelessness, substance use disorders, and limited access to healthcare. Nonpharmacological interventions are urgently needed to reduce dependence on opioids and unregulated drugs. myoActivation® is a novel systematic assessment and needling process designed to address MFD by targeting scars, fascia, and muscles using fine-gauge cutting-tip needles.
While this approach has shown promise in pediatric populations, its effectiveness had not been studied in adults with complex social and health challenges.
What They Did
The researchers conducted a prospective, longitudinal, observational pilot study at the Vancouver Community Pain Service (VCPS) in the DTES. They enrolled 35 adults with chronic pain (lasting more than 3 months) who were scheduled for myoActivation treatment as part of routine clinical care. Participants were assessed at baseline (Week 1) and followed up at 4, 12, and 24 weeks. The primary outcome was the PEG score (Pain, Enjoyment of life, and General Activity), a validated 3-item measure where lower scores indicate better outcomes.
A 30% reduction in PEG was considered clinically meaningful. Secondary outcomes included the Pain Catastrophizing Scale (PCS), the Pain Self-Efficacy Questionnaire (PSEQ), and self-reported changes in substance and analgesic medication use. The myoActivation process involved a detailed trauma history (Timeline of Lifetime Trauma), posture assessment, movement tests (BASE tests), and palpation to identify areas of MFD, followed by needling of scars, fascia, and muscle trigger points. Treatment was individualized, with a median of 4 sessions per participant.
The study used linear mixed-effects models to analyze changes over time while accounting for missing data.
What They Found
At baseline, participants had a median PEG score of 7.7 out of 10, indicating severe pain and interference with life. PEG scores improved significantly at every follow-up point: the mean difference from baseline was −1.8 at Week 4 (95% CI −2.6 to −0.9, p<0.001), −2.1 at Week 12 (95% CI −3.1 to −1.1, p<0.001), and −2.5 at Week 24 (95% CI −3.5 to −1.5, p<0.001). This represents a 32% improvement over the study period, exceeding the threshold for clinical significance. Pain catastrophizing (PCS) also improved, with a mean reduction of −5.6 points at Week 24 (95% CI −10.2 to −1.1, p=0.016), a 16% improvement.
Pain self-efficacy (PSEQ) improved by a mean of 3.5 points at Week 24 (95% CI 0.8 to 6.2, p=0.013), a 36% improvement. At Week 24, 9 out of 27 participants (33%) reported less unregulated drug use, and 8 out of 27 (30%) reported less analgesic medication use. Among participants treated for scars (26 out of 35, or 74%), 92% experienced somatic reactions and 54% had emotional responses including recall of traumatic memories. No serious adverse events were reported.
Follow-up rates were 77% at Week 4, 54% at Week 12, and 57% at Week 24, with some additional data obtained from electronic medical records.
What This Means
This pilot study provides preliminary evidence that myoActivation, a structured dry needling approach targeting scars, fascia, and muscles, can produce clinically meaningful and sustained improvements in pain, function, and quality of life for people with chronic pain who face significant social and health inequities. The 32% reduction in PEG scores at 24 weeks is particularly notable given the complexity of this population, where 69% had substance use disorders, 49% had PTSD, and 51% were homeless or in precarious housing. The reductions in self-reported unregulated drug use and analgesic medication use, while based on small numbers, suggest potential broader public health benefits in the context of an ongoing toxic drug crisis. The emotional and somatic responses to scar needling highlight the importance of trauma-informed care and the interconnectedness of physical and psychological trauma stored in fascial tissues.
However, the lack of a control group, small sample size, and significant loss to follow-up limit causal inference. The findings support further research, ideally with randomized controlled designs and larger samples, to confirm these promising results and to explore whether myoActivation could be scaled as a point-of-care intervention in primary care settings for underserved populations.
Key Findings
| Finding | Detail | Impact |
|---|---|---|
| Clinically significant and sustained improvement in pain and function | PEG scores improved by a mean difference of −2.5 (95% CI −3.5 to −1.5, p<0.001) at Week 24, representing a 32% improvement that exceeds the threshold for clinical meaningfulness | High |
| Reduced pain catastrophizing over 24 weeks | PCS scores improved by mean difference −5.6 (95% CI −10.2 to −1.1, p=0.016) at Week 24, a 16% improvement | Medium |
| Improved pain self-efficacy | PSEQ scores improved by mean difference 3.5 (95% CI 0.8–6.2, p=0.013) at Week 24, a 36% improvement | Medium |
| Potential reduction in substance and medication use | At 24 weeks, 9/27 (33%) reported less unregulated drug use and 8/27 (30%) reported less analgesic medication use, though these were self-reported outcomes with small numbers | Medium |
| High prevalence of trauma and emotional responses to scar needling | 74% of participants had scars treated; 92% had somatic reactions and 54% had emotional responses including traumatic memory recall, with no serious adverse events | Medium |
PEG scores improved by a mean difference of −2.5 (95% CI −3.5 to −1.5, p<0.001) at Week 24, representing a 32% improvement that exceeds the threshold for clinical meaningfulness
PCS scores improved by mean difference −5.6 (95% CI −10.2 to −1.1, p=0.016) at Week 24, a 16% improvement
PSEQ scores improved by mean difference 3.5 (95% CI 0.8–6.2, p=0.013) at Week 24, a 36% improvement
At 24 weeks, 9/27 (33%) reported less unregulated drug use and 8/27 (30%) reported less analgesic medication use, though these were self-reported outcomes with small numbers
74% of participants had scars treated; 92% had somatic reactions and 54% had emotional responses including traumatic memory recall, with no serious adverse events
Strengths
- Use of validated outcome measures (PEG, PCS, PSEQ) with established clinical meaningfulness thresholds
- Longitudinal follow-up over 24 weeks demonstrating sustained improvements
- Study conducted in real-world clinical setting with highly underserved population rarely included in pain research
- Linear mixed-effects analysis appropriately handled missing data and variable follow-up times
Limitations
- No control group limits ability to attribute improvements solely to myoActivation
- Small sample size (n=35) reduces generalizability and precision of estimates
- Significant loss to follow-up (43% at Week 24, though partially mitigated by EMR data)
- Single-center study in unique population may limit applicability to other settings
- Self-reported substance and medication use data subject to recall and social desirability bias
- Cannot isolate effects of myoActivation from other interdisciplinary services accessed by some participants
Key Takeaways for Patients
What This Means for You
- 01This study suggests that myoActivation needling may help reduce chronic pain and improve quality of life, even for people with very complex health and social challenges
- 02About one-third of participants reported using less unregulated drugs and less pain medication after treatment, though more research is needed to confirm this
- 03Treatment involving scar needling can trigger emotional memories or physical reactions like dizziness, so it should be done with trauma-informed care and support available
- 04The improvements were measured over 6 months, suggesting the benefits may last, but this was a small study without a comparison group, so larger studies are needed
- 05If you have chronic pain and a history of injuries, surgery, or trauma, asking your healthcare provider about myofascial dysfunction and whether needling approaches might help could be worthwhile
Read the Full Paper
Access the complete peer-reviewed study from Pain Research and Management
View Full Study