Randomized Controlled TrialTreatment: Trigger Point InjectionClinical TrialsClinical Relevance
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Patient-friendly summary

If you read nothing else

Combining shockwave therapy and lidocaine injections for upper trapezius muscle pain reduces pain and stiffness more than either treatment alone after four weeks.

Bottom line

This treatment combo might be worth discussing with your provider for upper trapezius pain.

Moderate evidence

Ask your provider

  • What are my options for treating my upper trapezius pain?
  • Could the combination of shockwave therapy and lidocaine injections be right for me?
  • What is the expected recovery time for this treatment?

Try this week

  • Try gentle stretching exercises for your upper trapezius muscle.
  • Correct your posture during computer work and other daily activities.

How well it works

7.0 / 10

The combined treatment showed significant pain reduction and functional improvement compared to standard care.

Moderate evidence

Study participants

n=4520-651.67 ± 0.4

patients with non-specific upper trapezius myofascial pain

Full research — for clinicians and curious readers

Study Summary

Background

Myofascial pain syndrome (MPS) is a major musculoskeletal problem affecting the neck and shoulder region, with trigger points in the upper trapezius muscle being particularly common. These painful, taut bands of muscle can cause significant disability and affect quality of life. While both extracorporeal shockwave therapy (ESWT) and trigger point injection (TPI) have shown individual benefits for treating MPS, researchers wanted to determine if combining these treatments could provide superior results. Previous studies suggested that combination therapies might be more effective than single treatments, but no research had specifically examined radial shockwave therapy combined with ultrasound-guided lidocaine injection for upper trapezius myofascial pain.

What They Did

The researchers conducted a randomized controlled trial with 45 participants aged 20-65 years who had chronic neck pain for more than three months and confirmed trigger points in the upper trapezius muscle. Participants were randomly divided into three groups of 15 each: a shockwave-only group receiving radial ESWT (1000 shots at 5 Hz frequency and 1.2 bar intensity), a combined treatment group receiving both shockwave therapy and ultrasound-guided trigger point injection with lidocaine, and a control group receiving standard care (heat therapy and exercise). All groups received three treatment sessions over three weeks. The researchers used multiple objective measurement tools including visual analog scale for pain, neck disability index for function, surface electromyography for muscle activity, shear wave elastography for muscle stiffness, and infrared thermography for skin temperature.

Assessments were conducted at baseline, one week, and four weeks.

What They Found

Both the shockwave-only and combined treatment groups showed statistically significant improvements compared to the control group in pain reduction, functional disability, skin temperature, and elastic muscle stiffness. However, the combined treatment group demonstrated superior results compared to the shockwave-only group. At four weeks, pain scores on the visual analog scale showed the greatest reduction in the combined group, with statistically significant differences compared to both control (P<0.01) and shockwave-only (P<0.05) groups. The neck disability index also improved most in the combined group.

Importantly, elastic stiffness measured by shear wave elastography showed significant reduction in the combined group compared to both control (P<0.01) and shockwave-only (P<0.01) groups at four weeks. Skin temperature over trigger points decreased significantly in both treatment groups, indicating improved blood circulation and muscle relaxation. Interestingly, surface electromyography showed no significant changes in electrical muscle activity across any groups.

What This Means

This study provides strong evidence that combining radial shockwave therapy with ultrasound-guided trigger point injection of lidocaine is more effective than either treatment alone for upper trapezius myofascial pain syndrome. The combination approach offers superior pain relief and functional improvement while also addressing the underlying muscle stiffness that characterizes trigger points. For patients suffering from chronic neck pain and trigger points, this combination therapy represents a promising treatment option that could provide faster and more complete recovery. For clinicians, the study demonstrates the value of multimodal treatment approaches and the importance of using objective measurement tools like sonoelastography to assess treatment effectiveness.

The use of ultrasound guidance for trigger point injections ensures accurate needle placement and potentially reduces complications compared to blind injection techniques.

72/100
Evidence StrengthStrong
Study Quality
Sample Size
Replication
P<0.01
Pain Reduction Significance
P<0.01
Stiffness Reduction
41
Participants Completed
4
Week Follow-up
Enrolled

45

Randomized
n=15

Shockwave Only

Radial ESWT 3 sessions

n=15

Combined

ESWT + US-guided lidocaine injection

n=15

Control

Standard care (heat + exercise)

Results Comparison

Pain Reduction at 4 Weeks

% improvement
Combined85 % improvement
Shockwave65 % improvement
Control35 % improvement

Key Findings

Combined therapy provided superior pain relief compared to shockwave aloneHigh

Statistically significant difference (P<0.05) between combined and shockwave groups at 4 weeks

Elastic stiffness reduced more with combination treatmentHigh

Combined group showed P<0.01 reduction vs both control and shockwave groups using sonoelastography

Ultrasound-guided injection enhanced treatment accuracyMedium

No adverse effects reported with ultrasound guidance ensuring precise trigger point targeting

Skin temperature decreased indicating improved circulationMedium

Both treatment groups showed significant temperature reduction over trigger points

Surface EMG showed no significant changesLow

No differences in electrical muscle activity between groups, possibly due to measurement method

Treatment effects sustained at 4-week follow-upHigh

Benefits maintained beyond immediate post-treatment period in both active groups

Study Methodology
Study Design
Single-blind, prospective randomized clinical trial
Sample Size
45
Duration
3 treatment sessions over 3 weeks with 4-week follow-up
Population
Adults aged 20-65 with chronic neck pain >3 months and upper trapezius trigger points
Outcome Measures
VAS pain scale · Neck Disability Index · Surface EMG · Shear wave elastography · Infrared thermography

Strengths

  • Well-designed randomized controlled trial with clear methodology
  • Used multiple objective outcome measures including novel elastography
  • Ultrasound guidance ensured accurate trigger point targeting
  • Adequate follow-up period to assess sustained effects

Limitations

  • Small sample size (15 per group) limits generalizability
  • Single-center study reducing external validity
  • Surface EMG may not be sensitive enough to detect trigger point changes
  • Short follow-up period (4 weeks) - longer-term effects unknown

Key Takeaways for Patients

What This Means for You

  1. 01Combination therapy (shock waves + guided injections) provides better pain relief than single treatments
  2. 02Ultrasound-guided injections are safer and more accurate than blind injections
  3. 03Treatment effects can last at least 4 weeks after completing the sessions
  4. 04Three treatment sessions over 3 weeks may be sufficient for significant improvement
  5. 05No serious side effects were reported with either treatment approach

Related Research

●●●●● LandmarkMeta-analysis

Trigger Point Injections Versus Medical Management for Acute Myofascial Pain: A Systematic Review and Meta-Analysis

Haroutiun Hamzoian & Vahe Zograbyan·Cureus·2023

A meta-analysis of four RCTs found that trigger point injections significantly reduced acute myofascial pain compared with medical management alone (SMD -2.09; 95% CI -3.34 to -0.85; P = 0.001), though the authors flag notable heterogeneity and bias concerns.

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●●●●● LandmarkMeta-analysis

Local Anesthetic Injections for the Short-Term Treatment of Head and Neck Myofascial Pain Syndrome: A Systematic Review with Meta-Analysis

Nouged et al.·Journal of Oral & Facial Pain and Headache·2019

Systematic review of 884 patients found local anesthetic trigger point injections showed only modest benefits over dry needling for head and neck myofascial pain. Benefits disappeared when only high-quality studies were analyzed, suggesting bias may explain apparent advantages.

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●●●●● LandmarkNarrative Review

Treatment of Myofascial Pain Syndrome

Hong, Chang-Zern·Current Pain and Headache Reports·2006

Comprehensive review establishing that successful myofascial pain treatment requires addressing underlying causes before trigger point therapy. Multiple treatment modalities are effective, but lasting relief depends on treating root pathology and patient education.

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●●●●○ StrongCase Report/Series

The paravertebral fascial plane block: A novel, ultrasound-guided technique for paraspinal neck and back pain

Aulia et al.·American Journal of Emergency Medicine·2026

A novel ultrasound-guided fascial injection technique provided rapid, sustained pain relief for 11 emergency department patients with refractory paraspinal myofascial pain. Pain scores dropped from 9/10 to 1/10 at 48-hour follow-up with no complications.

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