Narrative ReviewDiagnosis & AssessmentClinical RelevanceDOI
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Study Summary

Background

Myofascial pain syndrome (MPS) is an extremely common musculoskeletal condition, estimated to affect up to 85% of the general population depending on diagnostic criteria. It is characterized by localized muscle pain, tenderness, and trigger points—hyperirritable spots within muscle tissue or fascia that can cause significant disability and reduced quality of life. Common trigger point locations include the upper trapezius, levator scapulae, rhomboids, quadratus lumborum, and infraspinatus muscles. Despite its prevalence, MPS remains challenging to diagnose and treat effectively.

Traditional approaches rely heavily on physical palpation, which can be subjective and imprecise. Ultrasonography has emerged as a promising tool that could improve both the accuracy of diagnosis and the precision of treatments, but clinicians need clear guidance on how to apply it across different clinical scenarios involving MPS.

What They Did

This narrative review systematically searched four major medical databases (PubMed, Scopus, Embase, and Web of Science) through April 1, 2024, using search terms including "myofascial pain," "trigger point," "ultrasound," and "sonography." The authors included human studies that used ultrasound for either assessment or guided treatment of MPS, excluding animal studies, non-ultrasound imaging methods, studies without measurable clinical outcomes, and studies not focused on MPS patients. From this search, they identified and synthesized findings across seven key topic areas: (1) sonoelastography for upper trapezius MPS, (2) ultrasound-guided interfascial hydrodissection with visual feedback, (3) ultrasound-guided rhomboid interfascial plane blocks, (4) ultrasound-guided perimysium dissection for posterior shoulder MPS, (5) combined shockwave therapy with lidocaine injection for trapezius MPS, (6) various injection targets for MPS, and (7) ultrasound-guided delivery of local anesthetics and steroids for quadratus lumborum MPS.

What They Found

The review identified several clinically relevant findings from the included studies. Hao et al. (2023) found that shear-wave elastography could distinguish MPS patients from non-MPS controls, with area under the curve values of 0.899 for moderate pain and 0.983 for severe pain, and sensitivity of 86.27% and specificity of 62.07% for upper trapezius assessment. Suarez-Ramos et al.

(2023) demonstrated that ultrasound-guided interfascial hydrodissection with self-stretch exercises showed more significant effect sizes on visual analog scale pain scores compared to dry needling with self-stretch exercises in 46 participants, with improvements sustained up to 6 months. Hasuo et al. (2022) found that visual feedback during ultrasound-guided hydrodissection significantly enhanced treatment expectations and resulted in 67.7% of patients achieving 50% or greater improvement in numeric rating scale pain scores at 14 days, versus 36.6% in the non-visual feedback group. Ozyemisci Taskiran et al.

(2023) reported that ultrasound-guided rhomboid interfascial plane blocks produced significant pain reduction in approximately 90% of 23 patients at 1 week, 60-70% at 1 month, and 50% at 1 year. Lai et al. (2021) found that ultrasound-guided perimysium dissection in 57 patients resulted in 33.3% becoming pain-free and 56.1% achieving over 50% improvement, with mean VAS scores decreasing from 7.18±1.60 to 1.91±2.04. Anwar et al.

(2022) showed that combining extracorporeal shockwave therapy with ultrasound-guided trigger point injection of lidocaine produced more pronounced reduction in elastic stiffness at 4 weeks compared to shockwave alone. Barreto Silva et al. (2023) demonstrated that ultrasound-guided injection of levobupivacaine and triamcinolone for quadratus lumborum MPS in 90 participants produced pain improvements lasting up to 3 months and sustained at 6 months.

What This Means

This review establishes ultrasound as a versatile and valuable tool across the full spectrum of MPS care—from diagnosis through treatment. For clinicians, the key practical message is that ultrasound guidance can enhance both accuracy and safety when performing interventions for MPS. The technology allows real-time visualization of needle placement, helping avoid complications and ensuring precise delivery of treatments to target tissues. Specific techniques like interfascial hydrodissection, interfascial plane blocks, and perimysium dissection represent advanced applications that may offer advantages over conventional trigger point injections or dry needling alone.

The finding that visual feedback during procedures can enhance patient expectations and improve outcomes suggests a psychological component that clinicians can leverage. For patients, this means that seeking providers who use ultrasound-guided techniques may lead to better results with fewer risks. The sustained benefits reported at 6 months and even 1 year for some interventions also suggest that these approaches may provide durable relief rather than merely temporary symptom management. However, the review appropriately notes that many included studies were single-arm or small randomized trials, indicating that larger, more rigorous comparative studies are still needed to definitively establish optimal approaches for different MPS presentations.

45/100
Evidence StrengthModerate
Study Quality
Sample Size
Replication
85%
Population prevalence of MPS
0.983
AUC for severe pain detection via elastography
67.7%
Pain improvement with visual feedback
90%
Pain reduction at 1 week after rhomboid block

Key Findings

Shear-wave elastography can effectively distinguish MPS from non-MPS neck painHigh

Hao et al. (2023) found AUC values for upper trapezius mSWV of 0.578 for mild pain, 0.899 for moderate pain, and 0.983 for severe pain, with sensitivity of 86.27% and specificity of 62.07%

Visual feedback during ultrasound-guided hydrodissection enhances treatment outcomesHigh

Hasuo et al. (2022) reported 67.7% improvement in NRS pain scores by 50% or more in the visual feedback group versus 36.6% in the non-visual feedback group at 14 days

Ultrasound-guided interfascial hydrodissection outperforms dry needling for trapezius MPSHigh

Suarez-Ramos et al. (2023) found IH+SSE showed more significant effect size on VAS compared to DN+SSE in 46 participants, with sustained benefits up to 6 months

Rhomboid interfascial plane blocks provide durable pain reliefMedium

Ozyemisci Taskiran et al. (2023) observed significant pain reduction in approximately 90% of 23 patients at 1 week, 60-70% at 1 month, and 50% at 1 year

Perimysium dissection is effective for refractory posterior shoulder MPSMedium

Lai et al. (2021) found 33.3% of 57 patients became pain-free and 56.1% experienced over 50% improvement, with mean VAS decreasing from 7.18±1.60 to 1.91±2.04

Quadratus lumborum injections provide sustained pain reliefMedium

Barreto Silva et al. (2023) demonstrated pain improvements lasting up to 3 months and sustained at 6 months in 90 participants with quadratus lumborum MPS

Study Methodology
Study Design
Narrative review with systematic literature search
Sample Size
N/A
Duration
N/A
Population
Human subjects with myofascial pain syndrome across multiple anatomical regions
Outcome Measures
Varied by included study: VAS, NRS, EQ-5D-5L, shear-wave elastography, disability scales, quality of life measures

Strengths

  • Comprehensive coverage of both diagnostic and therapeutic ultrasound applications
  • Systematic search strategy across four major databases
  • Includes recent studies through 2024 with diverse intervention types
  • Practical clinical guidance with illustrative figures and technical descriptions

Limitations

  • Narrative review format without formal quality assessment or meta-analysis of included studies
  • Many included studies are single-arm or small sample size designs
  • Heterogeneous outcome measures and populations limit direct comparison across studies
  • No pooled effect estimates provided for any intervention

Key Takeaways for Patients

What This Means for You

  1. 01Ultrasound-guided treatments for muscle pain may be more precise and safer than blind injections
  2. 02Ask your provider if they use ultrasound when treating your trigger points—this technology can help them see exactly where to place the needle
  3. 03Some clinics can show you the ultrasound images during treatment, which research suggests may actually improve your results
  4. 04Pain relief from certain ultrasound-guided techniques may last 6 months or longer
  5. 05Different body areas (neck, shoulder, lower back) may respond best to different ultrasound-guided approaches

Read the Full Paper

Access the complete peer-reviewed study from Journal of Yeungnam Medical Science

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