Systematic ReviewPain Science & Central SensitizationSystematic Reviews & Meta-analysesClinical RelevanceDOI
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Patient-friendly summary

If you read nothing else

A review of fifteen studies found that Acceptance and Commitment Therapy (ACT) may help people with chronic pain accept their pain, function better, and feel less intense pain, though the evidence still has important limitations.

Bottom line

ACT appears to help with chronic pain across pain acceptance, functioning, and pain intensity, but the included studies had methodological weaknesses that may have overstated the benefits, so more rigorous trials are needed.

Preliminary evidence

Published

2021
5 years ago
Recent

Evidence hierarchy

Meta-analysis
Systematic Review ◀ this study
RCT
Cohort
Case-Control
Case Report
Expert Opinion

Study participants

Not reported (15 trials included)

Adults with chronic pain

Full research — for clinicians and curious readers

Study Summary

This systematic review evaluated the efficacy of Acceptance and Commitment Therapy (ACT) for managing chronic pain, searching the PubMed and EBSCO databases up to April 2020 and including fifteen trials. The authors report that results favored ACT for pain acceptance, functioning, and pain intensity, with small to large effect sizes; only a few studies assessed quality of life, and about half of those favored ACT. The review also looked at online ACT interventions in light of demands created by the COVID-19 pandemic. The authors conclude the evidence points in favor of ACT but caution that the included studies had methodological limitations that may have overestimated the effects.

50/100
Evidence StrengthModerate
Study Quality
Sample Size
Replication

Key Findings

Results favored ACT across several outcomesHigh

Across the fifteen included trials, results were in favor of ACT for pain acceptance, functioning, and pain intensity, with effect sizes ranging from small to large.

Quality-of-life evidence was limited and mixedMedium

Few studies evaluated quality of life, and of those that did, about half reported results favorable to ACT.

Methodological limitations may have overestimated effectsHigh

The authors note that the included studies suffered from methodological limitations that may have led to overestimated treatment effects, so robust trials are needed to clarify efficacy and identify which patients benefit most.

Online ACT delivery considered in context of COVID-19Medium

The review specifically focused part of its analysis on online ACT interventions, reflecting current demands due to the COVID-19 pandemic.

Study Methodology
Study Design
Systematic review of clinical trials, searching the PubMed and EBSCO databases up to April 2020
Sample Size
15 trials included (number of participants not reported)
Duration
Not reported
Population
Adults with chronic pain (specific conditions not reported in the abstract)
Outcome Measures
Pain acceptance · Functioning · Pain intensity · Quality of life

Strengths

  • Systematic search across two databases (PubMed and EBSCO) up to a defined cutoff (April 2020)
  • Assessed multiple clinically relevant outcomes (pain acceptance, functioning, pain intensity, quality of life)
  • Included a focused analysis of online ACT delivery, relevant to remote-care needs during the COVID-19 pandemic
  • Authors transparently acknowledge methodological limitations and the risk of overestimated effects

Limitations

  • Included studies suffered from methodological limitations that may have led to overestimated effects
  • Few studies evaluated quality of life, limiting conclusions for that outcome
  • The total number of participants, specific chronic-pain conditions, and effect-size values are not reported in this abstract
  • Published as a conference abstract (EPA Congress supplement), so detailed methods and risk-of-bias assessment are not available
  • The authors call for methodologically robust trials and note it is still unclear which patients benefit most

Key Takeaways for Patients

What This Means for You

  1. 01Acceptance and Commitment Therapy (ACT) is a psychological approach that helps people pursue meaningful, values-based activities even while living with ongoing pain, rather than focusing only on eliminating the pain.
  2. 02This review of fifteen trials suggests ACT may improve pain acceptance, day-to-day functioning, and pain intensity, though the size of the benefit varied.
  3. 03ACT can be delivered online, which became especially relevant during the COVID-19 pandemic.
  4. 04The evidence is encouraging but not definitive — the studies had limitations, so talk with your clinician about whether ACT fits your situation.

Read the Full Paper

Access the complete peer-reviewed study from European Psychiatry

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